Table 1 Summary of the CK8/18, CK5 and p63 expression profiles of the papillary lesions evaluated in the study
Marker | Papillary carcinoma (n=18) | Papilloma (n=24) | P-value |
|---|---|---|---|
CK8/18 | |||
Mean intensity score (range) | 227.3 (115–300) | 85.6 (10–220) | <0.0001 |
Mean % positive cells (range) | 95 (85–100) | 42 (10–85) | <0.0001 |
No. with ≥ 80% positive cells (%) | 18 (100) | 3 (13) | <0.0001 |
No. with ≥ 85% positive cells (%) | 18 (100) | 1 (4) | <0.0001 |
CK5 | |||
Mean intensity score (range) | 6.7 (0–20) | 106.9 (20–230) | <0.0001 |
Mean % positive cells (range) | 5 (0–15) | 58 (15–90) | <0.0001 |
p63 | |||
Negative (%) | 9 (50) | 0 (0) | <0.0002 |
Focal (%) | 9 (50) | 3 (13) | 0.014 |
Diffuse (%) | 0 (0) | 20 (79) | <0.0001 |
