Figure 4
From: New perspectives on the renal slit diaphragm protein podocin
Immunohistochemical detection suggests Sertoli cells to be the origin of testicular podocin. (a, b) Detection of WT-1 in nuclei of Sertoli cells (b) and podocin (a) within the membranes of sertoli cell extensions within a seminiferous tubule (APAAP, × 400). (c) The same primary antibody, but a biotinylated goat anti-rabbit IgG was used to detect podocin in a Sertoli cell tumor. (d) Podocin expression in renal glomeruli served as a positive control. Original magnification is shown in the lower right-hand corner of each image.
