Table 1 Comparison of patient demographics and clinical characteristics by TdT status and ETP status
Parameter | All patients (N=59) | TdT+ (N=52) | TdT− (N=7) | P-valuea | ETP, no (N=48) | ETP, yes (N=9) | P-valuea |
|---|---|---|---|---|---|---|---|
Age (years) | 0.27b | 0.56b | |||||
Median | 31 | 31 | 47 | 31 | 36 | ||
Range | 2–77 | 2–77 | 13–76 | 2–77 | 19–66 | ||
Age (years), n (%) | 0.19 | 0.58 | |||||
>18 | 52 (88.1) | 47 (90.4) | 5 (71.4) | 41 (85.4) | 9 (100) | ||
≤18 | 7 (11.9) | 5 (9.6) | 2 (28.6) | 7 (14.6) | 0 (0) | ||
Gender, n (%) | 0.66 | 1.00 | |||||
Male | 41 (69.5) | 37 (71.2) | 4 (57.1) | 34 (70.8) | 6 (66.7) | ||
Female | 18 (30.5) | 15 (28.8) | 3 (42.9) | 14 (29.2) | 3 (33.3) | ||
Initial disease site, n (%) | 0.70 | 0.07 | |||||
Extramedullary | 37 (62.7) | 32 (61.5) | 5 (71.4) | 32 (66.7) | 3 (33.3) | ||
Leukemia | 22 (37.3) | 20 (38.5) | 2 (28.6) | 16 (33.3) | 6 (66.7) | ||
WBC, n (%) | 0.62 | 1.00 | |||||
>100 K/μl | 12 (20.3) | 10 (19.2) | 2 (28.6) | 10 (20.8) | 2 (22.2) | ||
<100 K/μl | 47 (79.7) | 42 (80.8) | 5 (71.4) | 38 (79.2) | 7 (77.8) | ||
CNS, n (%) | 1.00 | 1.00 | |||||
Positive | 11 (18.6) | 10 (19.2) | 1 (14.3) | 9 (18.8) | 2 (22.2) | ||
Negative | 48 (81.4) | 42 (80.8) | 6 (85.7) | 39 (81.3) | 7 (77.8) | ||
ETP, n (%) | 0.07 | ||||||
Yes | 9 (15.8) | 6 (12.0) | 3 (42.9) | ||||
No | 48 (84.2) | 44 (88.0) | 4 (57.1) | ||||
Unknown | 2 | 0 | |||||
TdT, n (%) | 0.07 | ||||||
Negative | 7 (11.9) | 4 (8.3) | 3 (33.3) | ||||
Positive | 52 (88.1) | 44 (91.7) | 6 (66.7) | ||||
Karyotype, n (%) | 1.00 | 0.19 | |||||
Abnormal | 22 (51.2) | 19 (50.0) | 3 (60.0) | 17 (45.9) | 5 (83.3) | ||
Diploid | 21 (48.8) | 19 (50.0) | 2 (40.0) | 20 (54.1) | 1 (16.7) | ||
Unknown | 16 | 14 | 2 | 11 | 3 |
