Figure 1
From: TERT promoter mutations contribute to subset prognostication of lower-grade gliomas

Schematic diagram showing the positions of the two mutation hotspots (red), the primers for PCR (blue), the transcription start site (TSS) (black) and translation start site (ATG) (black) in the promoter region of TERT. Numbers denote the nucleotide positions on chromosome 5. The sequence at the top shows the wild-type sequence of the promoter region spanning the two hotspots (red).