Table 3 Univariate analysis in different subsets of lower-grade gliomas
From: TERT promoter mutations contribute to subset prognostication of lower-grade gliomas
Lower-grade glioma subset | TERT promoter | N | Median PFS (months) | P | Median OS (months) | P |
|---|---|---|---|---|---|---|
IDH mutated | ||||||
| Â | Mutated | 49 | 108.4 | 0.001 | 142.1 | <0.001 |
| Â | Wild type | 108 | 58 | Â | 74.4 | Â |
IDH-mutated-1p/19q codeleted | ||||||
| Â | Mutated | 28 | NR | 0.979 | 142.1 | 0.953 |
| Â | Wild type | 9 | NR | Â | NR | Â |
IDH-mutated-1p/19q intact | ||||||
| Â | Mutated | 19 | 108.4 | 0.027 | 141.5 | 0.004 |
| Â | Wild type | 97 | 56 | Â | 67 | Â |
IDH-mutated astrocytomas | ||||||
| Â | Mutated | 14 | NR | 0.001 | NR | 0.001 |
| Â | Wild type | 83 | 56 | Â | 67 | Â |
IDH wild type | ||||||
| Â | Mutated | 16 | 7 | 0.001 | 14.1 | 0.001 |
| Â | Wild type | 58 | 25.6 | Â | 36 | Â |
IDH wild-type astrocytomas | ||||||
| Â | Mutated | 16 | 7 | 0.007 | 14.1 | 0.008 |
| Â | Wild type | 49 | 20.3 | Â | 24 | Â |
