Table 2 Clinicopathologic features related to ANXA10 expression

From: Aberrant expression of annexin A10 is closely related to gastric phenotype in serrated pathway to colorectal carcinoma

 

ANXA10 positive N=36

ANXA10 negative N=87

Odds ratio

P-value

Location (n (%))

  

3.72

0.001

 Right

25 (69%)

33 (38%)

  

 Left

11 (31%)

54 (62%)

  

Tumor differentiation (n (%))

  

—

<0.0001

 Well

4 (11%)

42 (48%)

  

 Moderate

8 (22%)

26 (30%)

  

 Poor

24 (67%)

19 (22%)

  

Tumor histology (n (%))

    

 Mucinous differentiation

13 (36%)

22 (25%)

1.67

0.226

 Medullary histology

2 (6%)

5 (6%)

0.97

0.967

 Signet ring histology

5 (14%)

0 (0%)

—

<0.0001

Pathologic features of invasive carcinoma (n (%))

    

 Crohn’s-like reaction

30 (83%)

42 (48%)

5.36

<0.0001

 Tumor-infiltrating lymphocytes

13 (36%)

20 (23%)

1.89

0.135

 Dirty necrosis

10 (28%)

60 (69%)

0.17

<0.0001

MUC5AC expression

    

 Positive

33 (92%)

34 (39%)

17.15

<0.0001

 Negative

3 (8%)

53 (61%)

  

MUC6 expression

  

4.69

<0.0001

 Positive

21 (58%)

20 (23%)

  

 Negative

15 (42%)

67 (77%)

  

CDX2 expression

  

7.54

<0.0001

 <50%

22 (61%)

15 (17%)

  

 ≧50%

14 (39%)

72 (83%)

  

Molecular subgroup of carcinoma

  

—

<0.0001

 Group 1 (n=18)

10 (28%)

8 (9%)

  

 Group 2 (n=40)

24 (67%)

16 (18%)

  

 Group 3 (n=55)

0 (0%)

55 (63%)

  

 Group 4 (n=10)

2 (6%)

8 (9%)

  
  1. Abbreviation: ANXA10, annexin A10.