Figure 2 | Modern Pathology

Figure 2

From: Comprehensive screening of alternative lengthening of telomeres phenotype and loss of ATRX expression in sarcomas

Figure 2

The anaplastic embryonal rhabdomyosarcoma (a1) with loss of ATRX (a2) but not DAXX (a3) expression positive for alternative lengthening of telomeres phenotype (a4). A hypercellular nodule in a gastrointestinal stromal tumor (b1) with loss of ATRX (b2) but not DAXX (b3) expression positive for alternative lengthening of telomeres phenotype (b4). The only myxofibrosarcoma (c1) deficient for ATRX (c2). An osteosarcoma (c3) deficient for ATRX (c4). a1, b1, c1, and c3: hematoxylin and eosin stain; a4 and b4: telomere fluorescence in situ hybridization. Original magnification: a1-3, b1-3, and c1-4: × 200; a4 and b4: × 1000.

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