Table 3 Differentially expressed genes distinguishing keratoacanthoma from normal skin

From: Keratoacanthoma and squamous cell carcinoma are distinct from a molecular perspective

Ref Seq

Symbol/Gene

Fold Change

Upregulated genes

 NR_002819

MALAT1: metastasis-associated lung adenocarcinoma transcript 1 (nonprotein coding)

216.93

 NM_002964

S100A8: S100 calcium-binding protein A8

156.65

 NM_004065

CDR1: cerebellar degeneration-related protein 1, 34 kDa

146.93

 NM_001145160 /// NM_003290

TPM4: tropomyosin 4

109.70

 NM_006888

CALM1: calmodulin 1 (phosphorylase kinase, delta)

73.16

 NM_012153

EHF: ets homologous factor

69.28

 NM_006815

TMED2: transmembrane emp24 domain trafficking protein 2

66.98

 NM_001031827

BOLA2: BolA homolog 2 (E. coli)

63.00

 NR_000012

SNORA68: small nucleolar RNA, H/ACA box 68

55.07

 NM_001114978 /// NM_001114979 /// NM_001114980 /// NM_001114981 /// NM_001114982

TP63: tumor protein p63

46.38

Downregulated genes

 NM_002411

SCGB2A2: secretoglobin, family 2A, member 2

−132.56

 NM_053283

DCD: dermcidin

−109.61

 NM_003251

THRSP: thyroid hormone responsive (SPOT14 homolog, rat)

−64.04

 NM_004797

ADIPOQadiponectin: C1Q and collagen domain containing

−60.42

 NM_000668

ADH1B: alcohol dehydrogenase 1B (class I), beta polypeptide

−58.21

 NM_000517 /// NM_000558

HBA1 /// HBA2: hemoglobin, alpha 1 /// hemoglobin, alpha 2

−49.82

 NM_006551

SCGB1D2: secretoglobin, family 1D, member 2

−48.13

 NM_020692

GALNTL1: UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase

−42.47

 NM_173833

SCARA5: Scavenger receptor class A, member 5 (putative)

−37.36

 NM_001143981 /// NM_001143982 /// NM_001143983 /// NM_145234

CHRDL1: chordin-like 1

−35.17