Table 1 BAP1 immunoreactivity in tissues biopsies

From: BAP1 (BRCA1-associated protein 1) is a highly specific marker for differentiating mesothelioma from reactive mesothelial proliferations

Diagnosis

No. of cases

BAP1 loss (%)

Normal mesothelium

11

0/11 (0)

Benign mesothelial tumor

12

0/12 (0)

 Benign multicystic mesothelioma

3

0/3

 Benign papillary mesothelioma

2

0/2

 Adenomatoid tumor

7

0/7

Malignant mesothelioma

212

139/212 (66)

 Epithelioid

184

128/184 (70)

 Biphasic

15

9/15 (60)

 Sarcomatoid

8

1/8 (13)

 Desmoplastic

5

1/5 (20)

Reactive mesothelial proliferation

42

6/42 (14)

 Simple

27

2/27 (7) a

 Atypical

15

4/15 (27) a

  1. aAll BAP1-negative cases developed malignant mesothelioma.