Table 3 BAP1 immunoreactivity in cytological and cell-block samples

From: BAP1 (BRCA1-associated protein 1) is a highly specific marker for differentiating mesothelioma from reactive mesothelial proliferations

Diagnosis

No. of cases

BAP1 loss (%)

Benign mesothelial reaction

17

0/17 (0)

 Inflammatory

15

0/15 (0)

 Lung adenocarcinoma

2

0/2 (0)

Malignant mesothelioma

45

29/45 (64)

Atypical mesothelial cells of indeterminate origin

8

6/8a (75)

  1. aAll BAP1-negative cases developed malignant mesothelioma.
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