Table 4 BAP1 immunoreactivity in lung and ovary carcinomas and in epithelioid hemangioendothelioma of the lung

From: BAP1 (BRCA1-associated protein 1) is a highly specific marker for differentiating mesothelioma from reactive mesothelial proliferations

  

BAP1

Diagnosis

No. of cases

Positive

Negative

Lung

 Adenocarcinoma

184

182a

2

Acinar/acinar+lepidic

111

110

1

Solid

14

13

1

Solid+lepidic or acinar

22

22

0

Lepidic

19

19

0

Mucinous

9

9

0

Micropapillary

7

7

0

Papillary

2

2

0

 Squamous cell carcinoma

21

21

0

 Epithelioid hemangioendothelioma

8

8

0

Ovary

 Serous carcinoma

71

71a

0

 Endometrioid carcinoma

11

11

0

 Undifferentiated carcinoma

4

4

0

 Clear cell carcinoma

6

6a

0

 Mucinous carcinoma

3

3

0

  1. aScattered BAP1-negative tumor cells within predominant BAP1-positive tumor cells were identified in one or two cores from 18 cases of lung adenocarcinoma (13), serous (4), and clear cell (1) ovarian carcinoma, respectively.
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