Table 2 Performance metrics for PTEN immunohistochemistry compared to gold standard PTEN FISH

From: Analytic validation of a clinical-grade PTEN immunohistochemistry assay in prostate cancer by comparison with PTEN FISH

 

%

n

Specificity

91

549/602

Sensitivity for homozygous deletion

97

65/57

Sensitivity for hemizygous deletion

65

40/62

Positive predictive value

66

105/158

Negative predictive value

96

549/573