Table 3 Comparison of PTEN immunohistochemistry and FISH results on tissue microarray cores and standard tissue section slides
Case | Tissue microarray PTEN immunohistochemistry | Standard slide PTEN immunohistochemistry | Tissue microarray PTEN FISH | Standard slide PTEN FISH |
|---|---|---|---|---|
1 | Intact | Intact | Intact | Intact |
2 | Intact | Heterogeneous loss | Intact | Intact |
3 | Intact | Intact | Intact | Intact |
4 | Intact | Intact | Intact | Failure |
5 | Heterogeneous loss | Heterogeneous loss | Homo-deletion | Hemi-deletion and homo-deletion |
6 | Heterogeneous loss | Heterogeneous loss | Homo-deletion | Homo-deletion |
7 | Heterogeneous loss | Heterogeneous loss | Homo-deletion | Homo-deletion |
8 | Heterogeneous loss | Heterogeneous loss | Intact | Intact |
9 | Heterogeneous loss | Heterogeneous loss | Intact | Intact |
10 | Heterogeneous loss | Intact | Intact | Intact |
11 | Heterogeneous loss | Heterogeneous loss | Intact | Intact |
12 | Heterogeneous loss | Intact | Intact | Hemi-deletion |
13 | Heterogeneous loss | Heterogeneous loss | Intact | Homo |
14 | Heterogeneous loss | Heterogeneous loss | Intact | Homo |
15 | Heterogeneous loss | Heterogeneous loss | Intact | Hemi-deletion of WAPAL |
16 | Homogeneous loss | Homogeneous loss | Hemi-deletion | Hemi-deletion |
17 | Homogeneous loss | Heterogeneous loss | Intact | Hemi-deletion |
18 | ambiguous | Intact | Intact | Intact |
19 | Heterogeneous loss | Heterogeneous loss | Core missing | Intact |
20 | Heterogeneous loss | Heterogeneous loss | Core missing | Intact |
