Table 1 Descriptive summary of MZ and DZ twins in Swedish and Danish twin samples, stratified by sex

From: Genetic overlap between type 2 diabetes and depression in Swedish and Danish twin registries

Sample

 

Swedish

Danish

  

Males

Females

Males

Females

Number of paired twins

Number of single twins

MZ

6524

2335

9270

2131

11 006

59

11 110

59

 

DZ

7440

3757

9770

3421

19 538

130

17 640

113

 

Opposite-sex

17 078

6880

 

34 900

848

 
 

Total

50 082

18 524

 

94 194

1209

 

Age, mean (s.d.)

MZ

54.9 (17.9)

55.0 (18.7)

58.3 (16.8)

59.5 (18.3)

 

DZ

60.3 (16.8)

61.3 (18.0)

60.5 (16.1)

63.0 (17.7)

 

Opposite-sex

59.2 (16.5)

 

58.6 (15.7)

 
 

Total

58.5 (17.6)

 

60.0 (16.8)

 

Prevalence of T2DM (%)a

MZ

5.5

4.2

4.1

3.3

 

DZ

6.9

5.2

4.7

4.2

 

Opposite-sex

5.8

 

3.1

 

Prevalence of depression (%)a

MZ

3.7

5.8

2.8

4.7

 

DZ

3.7

5.7

3.2

5.7

 

Opposite-sex

4.9

 

3.8

 

Proband wise concordance rate for T2DM

(Number of concordant pair, discordant pair)

MZ

0.42

(69, 190)

0.43

(75, 195)

0.37

(83, 287)

0.33

(60, 247)

 

DZ

0.20

(49, 398)

0.23

(53, 350)

0.14

(64, 764)

0.18

(66, 605)

 

Opposite-sex

0.18

(91, 813)

 

0.13

(66, 886)

 

Proband wise concordance rate for depression

(Number of concordant pair, discordant pair)

MZ

0.21

(22,174)

0.22

(57, 399)

0.19

(29, 243)

0.23

(59, 400)

 

DZ

0.06

(8, 249)

0.05

(13, 489)

0.05

(16, 591)

0.16

(77, 837)

 

Opposite-sex

0.09

(37, 706)

 

0.09

(61, 1170)

 
  1. Abbreviations: DZ, dizygotic twins; MZ, monozygotic twins; T2DM, type 2 diabetes.
  2. aIn the genetic modelling, the thresholds and other estimates apply to the sample at mean age. For example, with the effect of age being estimated at −0.03 for males in the Swedish Twin Registry, T2DM prevalence rates will be 1.3% at age 40 and 9.0% at age 70.