Figure 4: Analysis of sequence comparison of three species.
From: Numerous potentially functional but non-genic conserved sequences on human chromosome 21
a, Proportional representation of the species-specific nucleotide substitutions in human (blue), rabbit (red) and mouse (yellow). Each bar represents one of the 111 regions sequenced in rabbit, ordered by their position on human chromosome 21 (centromere to telomere). Note the apparent heterogeneity. b, Distribution of the difference in the percentage (G+C) content between human and mouse (%(G+C)human - %(G+C)mouse). The trend towards higher (G+C) content in mouse is obvious by the shift of the distribution to the left. c, Species-specific substitution counts in human, mouse and rabbit. The (A + T) to (G+C) bias in mouse and rabbit is evident.
