Figure 1: Pathological examination of the lungs of infected cynomolgus macaques.
From: In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses
a–h, Representative pathological images of CA04-infected (macaque no. 1, a–d), KUTK-4-infected (macaque no. 7, e–g) and mock-infected (h) lungs on day 3 after infection. One or two sections per lung lobe were examined. Representative findings are shown to depict the distribution of lesions in the sections (shown as cross-sections placed next to illustrations of each lung lobe), with or without viral antigen, as follows: brown, severe lung lesion containing moderate to many viral-antigen-positive cells; pink, mild lung lesions containing a few viral-antigen-positive cells; blue, lung lesions with alveolar wall thickening, with remaining air spaces unaffected. Original magnification: a, e, h, ×40; b–d, f, g, ×400.
