Figure 4: The contributions of mutational signatures to individual cancers of selected cancer types.

Each bar represents a typical selected sample from the respective cancer type and the vertical axis denotes the number of mutations per megabase. Contributions across all cancer samples could be found in Supplementary Figs 29–58. Summary of the total contributions for all operative mutational processes in a cancer type can be found in Supplementary Figs 59–88. ‘Other’ indicates mutational signatures for which we were not able to perform validation or for which validation failed (Supplementary Figs 24–28).