Figure 5: Selected mutational signatures with strong transcriptional strand bias.
Mutations are shown according to the 192 mutation classification incorporating the substitution type, the sequence context immediately 5′ and 3′ to the mutated base and whether the mutated pyrimidine is on the transcribed or untranscribed strand. The mutation types are displayed on the horizontal axis, whereas the vertical axis depicts the percentage of mutations attributed to a specific mutation type. A higher resolution version of all mutational signatures with strong transcriptional strand bias is found respectively in Supplementary Figs 89–95.
