Extended Data Figure 8: Dynamics of dendritic spines in the hindlimb area during learning of the lever-press task.
From: Emergence of reproducible spatiotemporal activity during motor learning
Summary of dendritic spine dynamics in the hindlimb area during control period (7 days before training) and subsequent 7 days of training. Mice were water restricted in both conditions. Top: spine additions (black) and eliminations (grey) in each session. For control sessions, data from all sessions are combined. Bottom: total spine number across sessions. Values are normalized to the total spine number in session 1 in each condition. Unlike the forelimb area, the density of dendritic spines in the hindlimb area is relatively stable during learning (P = 0.07, comparisons between control versus training sessions 4–7, Wilcoxon rank sum test). All error bars are s.e.m.
