Extended Data Figure 5: Characterization of Masc.
From: A single female-specific piRNA is the primary determiner of sex in the silkworm
a, Structure of Masc mRNA. Five Masc transcripts (A–E) that encode full-length Masc proteins but show unique splicing patterns in the 3′-untranslated region as well as one transcript (F) that encodes a truncated Masc protein are found. b, Domain structure of the Masc protein. The hexagons show the location of two CCCH-type zinc finger domains. The amino acid sequences of these domains are shown below. The conserved CCCH residues are shown in red. c, Phylogenetic analysis of Masc proteins. The neighbour-joining tree was generated using the amino acid sequences of zinc finger domains from proteins showing homology to Masc. The numbers on the internal branches represent the support value in the bootstraps of 1,000 replicates.
