Extended Data Figure 3: Myc binds active enhancers.
From: Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis
a, Representative snapshots of Myc-bound regions in the genome. ChIP-seq tracks are shown for Myc, RNAPII, H3K4me3, H3K4me1 and H3K27ac in the indicated samples (C, P and T1 as a representative tumour). CGI, CpG island. Promoter and enhancer regions, on the basis of annotation and chromatin features, are indicated. b, List of the domains (amplicon) previously tested and validated (last column) as B-cell enhancers14. Bound C, P, T: Myc-binding status in our data set (y, yes; n, no). Note that the two domains listed in bold are also displayed next to the table (Bst1 and Bcl7a loci).
