Extended Data Figure 3: Reaction with 8-oxo-dGTP opposite templating cytosine.
From: Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide
a, Focused view of the active site following a 40 s soak is shown with key residues indicated; density has been removed for clarity (see Fig. 2e for density). b, An omit map (3σ) for Cag is shown. Coordinating waters are shown in blue (distances in ångströms). c, An omit map (3σ) for Mgp is shown.
