A high-resolution crystal structure of the HIV-1 Env trimer proteins, in their form before they fuse with target cells, will aid the design of vaccines that elicit protective immune responses to this protein complex. See Article p.455
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to the full article PDF.
USD 39.95
Prices may be subject to local taxes which are calculated during checkout

References
Kwong, P. D. et al. Nature 393, 648–659 (1998).
Julien, J.-P. et al. Science 342, 1477–1483 (2013).
Lyumkis, D. et al. Science 342, 1484–1490 (2013).
Pancera, M. et al. Nature 514, 455–461 (2014).
Klasse, P. J. Virology 369, 245–262 (2007).
Sanders, R. W. et al. PLoS Pathog. 9, e1003618 (2013).
Forsell, M. N., Schief, W. R. & Wyatt, R. T. Curr. Opin. HIV AIDS 4, 380–387 (2009).
Guttman, M. & Lee, K. K. J. Virol. 87, 11462–11475 (2013).
Ringe, R. P. et al. Proc. Natl Acad. Sci. USA 110, 18256–18261 (2013).
Tran, K. et al. Proc. Natl Acad. Sci. USA 111, E738–E747 (2014).
Sanders, R. W. et al. J. Virol. 76, 8875–8889 (2002).
Binley, J. M. et al. J. Virol. 74, 627–643 (2000).
Medina-Ramírez, M., Sanders, R. W. & Klasse, P. J. Expert Rev. Vaccines 13, 449–452 (2014).
Schiller, J. & Chackerian, B. PLoS Pathog. 10, e1004254 (2014).
McLellan, J. S. et al. Science 342, 592–598 (2013).
Author information
Authors and Affiliations
Corresponding authors
Rights and permissions
About this article
Cite this article
Sanders, R., Moore, J. A stamp on the envelope. Nature 514, 437–438 (2014). https://doi.org/10.1038/nature13926
Published:
Issue date:
DOI: https://doi.org/10.1038/nature13926