Blocking the activity of macrophages may delay the spread of cancer. But new findings show that these immune cells can rapidly rebound to tumours after therapy withdrawal, accelerating lethal metastasis in mice. See Letter p.130
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Keklikoglou, I., De Palma, M. Metastasis risk after anti-macrophage therapy. Nature 515, 46–47 (2014). https://doi.org/10.1038/nature13931
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DOI: https://doi.org/10.1038/nature13931
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