Extended Data Figure 2: LAR structure, sequence alignment and pulldown analysis.
From: Modulation of the proteoglycan receptor PTPσ promotes recovery after spinal cord injury
a, BLAST alignment of the known sequences of mouse, rat and human LAR, PTPσ, PTPδ and PTPμ. The wedge domain of each protein is aligned within the box. b, The tandem intracellular phosphatase domains of human LAR with the previously characterized wedge domain (red)14. c, d, Pulldown of recombinant PTPσ with biotinylated (b)ISP or ILP. e, f, Eluted lysate after pulldown was probed with antibodies against either LAR or pan-NgRs. Input is 10% lysate control.
