Extended Data Table 2 Enrichments of 49 WHRadjBMI signal SNPs with metabolic and anthropometric traits

From: New genetic loci link adipose and insulin biology to body fat distribution

  1. The 49 WHRadjBMI SNPs were tested for association with other traits by GWAS meta-analyses performed by other groups (see Methods). The maximum sample size available is shown overall or separately for cases/controls. N indicates the number of the total SNPs for which the WHRadjBMI-increasing allele is associated with the trait in the concordant direction (increased levels, except for HDL-C, adiponectin and BMI). One-sided binomial P values test whether this number is greater than expected by chance (null P = 0.5 and null P = 0.025, respectively). The tests do not account for correlation between WHRadjBMI and the tested traits. P values representing significant column-wise enrichment (P < 0.05/23 tests) are marked in bold.
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