Extended Data Table 4 Candidate genes at new loci associated with additional waist and hip-related traits

From: New genetic loci link adipose and insulin biology to body fat distribution

  1. Candidate genes for loci shown on Table 3 based on secondary analyses or literature review. Further details are provided in other Supplementary Tables and the Supplementary Note. Loci are shown in order of chromosome and position.
  2. *Gene transcript levels associated with SNP genotype (eQTL) in the indicated tissue(s).
  3. †Genes in pathways identified as enriched by GRAIL analysis.
  4. ‡Strongest candidate genes identified based on manual literature review.
  5. §Traits associated at P < 5 × 10−8 in GWAS lookups or in the GWAS catalogue using the index SNP or a proxy in high LD (r2 > 0.7), and the genes(s) named in those reports.
  6. ∥Non-synonymous variants (nsSNPs) and copy number variants (CNVs) with tag SNPs in high LD with index SNP based on a 1000 Genomes CEU reference panel. DEPICT analysis was not performed for loci associated with these traits.
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