Extended Data Figure 8: Regional plots of genome‐wide significant loci from single‐SNV association tests from lumbar spine BMD. | Nature

Extended Data Figure 8: Regional plots of genome‐wide significant loci from single‐SNV association tests from lumbar spine BMD.

From: Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture

Extended Data Figure 8: Regional plots of genome‐wide significant loci from single‐SNV association tests from lumbar spine BMD.The alternative text for this image may have been generated using AI.

Each regional plot depicts SNVs within 1 Mb of a locus’ lead SNV (x axis) and their associated meta‐analysis P value (−log10). SNVs are colour coded according to r2 with the lead SNV (labelled, r2 calculated from UK10K whole genome sequencing data set). Recombination rate (blue line), and the position of genes, their exons and the direction of transcription are also displayed (below plot).

Back to article page