Extended Data Figure 7: Evidence of endothelial cells in the kidney organoid.
From: Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis
a, Immunofluorescence of day 11 kidney organoids showing the presence of CD31+KDR+ endothelial cells surrounding NPHS1+ glomeruli. Scale bar, 100 μm. b, Two representative images demonstrating the expression of another endothelium marker SOX17 in CD31+ endothelial cells. Scale bars, 100 μm. c, Immunofluorescence of day 18 kidney organoids displaying endothelia with lumen formation, as indicated by asterisks. This image also shows the endothelial invasion into a glomerulus. Scale bar, 100 μm.
