Extended Data Figure 6: Growth curves and spot assays.
From: The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions
Wild-type (black) and alkD-knockout (red) strains of B. anthracis were treated with varying concentrations of mMS and YTM. Control experiments contained no drug. Deletion of AlkD caused no observable phenotype with mMS but resulted in increased sensitivity to YTM. a, mMS treatment. b, YTM treatment. Error bars represent the s.e.m. from three replicate growth curves. Spot assays were performed in duplicate.
