Extended Data Figure 8: The plug domains in SecY channels.
From: Crystal structure of a substrate-engaged SecY protein-translocation channel
a, The plugs in channels of different organisms have different structures. Shown are side views with the plugs in yellow and pore residues as red spheres. PDB accession numbers are given below the names of the organisms. For the G. thermodenitrificans channel, the translocating peptide segment was omitted. b, In the inactive T. maritima SecY channel, the plug (in yellow) is at the front of the channel, partly sealing the periplasmic side of the lateral gate. Shown is a side view in a surface representation, with hydrophilic and hydrophobic residues in blue and orange, respectively.
