Extended Data Figure 2: Surface charge distribution of gp9.
From: The bacteriophage ϕ29 tail possesses a pore-forming loop for cell membrane penetration
a, Diagram showing the surface charge distribution of gp9Δ417–491. Negative and positive electrostatic potentials are coloured red and blue, respectively. The monomers within the hexamer interact with each other primarily through hydrogen bonds and hydrophobic interactions. The outer cylindrical surface of the tube is hydrophilic. The top and bottom surfaces of the tube have substantially different features. The top surface on the N-β-barrel domain side is largely hydrophobic, whereas the bottom surface on the tip β-domain side is rich in negatively charged residues. b, Diagram showing the surface charge distribution of the interior L loops. Negative and positive electrostatic potentials are coloured as in a. A thin central slice of the tube is shown and coloured dark grey to indicate the tube boundary.
