Extended Data Figure 9: Schematic for convergence of anticipatory and homeostatic signals at SFONos1 thirst neurons. | Nature

Extended Data Figure 9: Schematic for convergence of anticipatory and homeostatic signals at SFONos1 thirst neurons.

From: Thirst neurons anticipate the homeostatic consequences of eating and drinking

Extended Data Figure 9: Schematic for convergence of anticipatory and homeostatic signals at SFONos1 thirst neurons.

SFONos1 neurons monitor the composition of the blood by sensing plasma osmolarity and, via angiotensin, plasma volume and pressure. SFONos1 neurons predict the future state of the blood by integrating temperature-dependent inputs from the mouth and osmolarity-dependent inputs from the gut during drinking, and angiotensin- and osmolarity-independent inputs from the mouth/gut during eating. Illustration from National Institute of Diabetes and Digestive and Kidney Diseases, US National Institutes of Health.

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