Extended Data Figure 6: Non-canonical distal H3K4me3 in oocytes correlates with DNA hypomethylation.
From: Allelic reprogramming of the histone modification H3K4me3 in early mammalian development
a, Box plots showing the CpG density of H3K4me3 promoter and distal peaks in early embryos, mES cells, and the cortex. b, Pie charts showing the percentage of the genome covered by PMDs (left) and the percentage of distal H3K4me3 marked regions covered by PMDs (right) in MII oocytes. c, A global view of H3K4me3 promoter and distal peak density of chr12 in MII oocytes (top). Gene densities and PMD densities are also shown (bottom). Three gene desert regions are shaded. d, DNA methylation levels around active genes are shown for those in embryonic day 16.5 (E16.5) female PGCs37, day 14 oocytes, and MII oocytes14.
