Extended Data Figure 8: ncH3K4me3 is not found in zebrafish.
From: Allelic reprogramming of the histone modification H3K4me3 in early mammalian development
a, A snapshot of the UCSC genome browser shows the global view of H3K4me3 enrichment in oocytes (this study), the dome stage embryos38, 48 hours post fertilization (hpf) embryos39 and DNA methylation level40 for various zebrafish developmental stages. b, The genomic distributions are shown for the H3K4me3 peaks in zebrafish oocytes, embryos at the dome stage38 and 48 hpf embryos39. c, Box plots showing the CpG densities of H3K4me3 promoter peaks in zebrafish oocytes, embryos at the dome stage38 and embryos at 48 hpf39. A random set of peaks that match the lengths of H3K4me3 peaks on the same chromosomes were used as a control in the analysis. d, Violin plots showing the distributions of DNA methylation levels from gametes to somatic tissues in zebrafish (left panel) or mice (right panel). e, Box plot showing the lengths of distal PMDs in zebrafish and mouse oocytes, sperms, and somatic tissues. f, Bar chart shows the percentages of the genome covered by distal PMDs in oocytes, sperms and somatic tissues in zebrafish or mouse.
