Extended Data Figure 5: Flexibility of ECD and AHD in the sCT–CTR–Gs complex.
From: Phase-plate cryo-EM structure of a class B GPCR–G-protein complex

Representative maps from three-dimensional classification showing the dynamics of the CTR ECD and Gαs AHD. The overlaid maps are shown from top and side views. In the right panel the blue, green, purple and red density maps show the four 3D classifications. These are overlayed on the left to demonstrate the observed flexibility of the Gαs AHD and the CTR ECD.