Extended Data Figure 1: Fraction of DNMs of paternal origin.
From: Parental influence on human germline de novo mutations in 1,548 trios from Iceland
a, b, Fraction of DNMs from father per proband. c, d, Fraction of DNMs from father per proband against parental age difference at conception (father’s age − mother’s age). e, f, Paternal age at conception against maternal age at conception. In b, d, and f, all probands with phased DNMs were used; meanwhile, in a, c, and e, the analysis was restricted to 225 three-generation probands. The vertical bars in c and d represent 95% confidence intervals using a normal approximation.
