Extended Data Figure 6: Effector-stage de novo DNA methylation is enriched at genes that regulate effector and memory T cell differentiation. | Nature

Extended Data Figure 6: Effector-stage de novo DNA methylation is enriched at genes that regulate effector and memory T cell differentiation.

From: Effector CD8 T cells dedifferentiate into long-lived memory cells

Extended Data Figure 6

a, Normalized Dnmt3a-mediated de novo methylation at CpG sites in the Lef1 and Il6st loci from WGBS datasets. b, Summary of maintenance methylated regions in wild-type and Dnmt3a cKO effector WGBS datasets. c, Connectivity plot showing IPA-predicted interactions of ID2 and ID3 with Dnmt3a-targeted loci.

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