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  • Review Article
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New Perspectives On Catalytic Antibodies

Bio/Technology volume 9, pages 258–262 (1991)Cite this article

Abstract

This review will give examples of the structure-function relationships used in the design of catalytic antibodies, including not only ligand or hapten-based approaches but also recent developments in the generation of catalytic antibodies through protein engineering. Last, a thermodynamic analysis is presented, which confirms that some antibodies do indeed catalyze their transformations by stabilizing transition states.

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Authors and Affiliations

  1. Department of Chemistry and Biochemistry, University of Colorado, Boulder, Colorado, 80309-0215

    Jeffrey W. Jacobs

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  1. Jeffrey W. Jacobs
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Jacobs, J. New Perspectives On Catalytic Antibodies. Nat Biotechnol 9, 258–262 (1991). https://doi.org/10.1038/nbt0391-258

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