New strategies for targeting mammalian genes have produced the first knockout rats and a faster way of generating knockout mice.
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References
Zan, Y. et al. Nat. Biotechnol. 21, 645–651 (2003).
Valenzuela, D.M. et al. Nat. Biotechnol. 21, 652–659 (2003).
Coghill, E.L. et al. Nat. Genet. 30, 255–256 (2002).
Chen, Y., Schimenti, J. & Magnuson, T. Mamm. Genome 11, 598–602 (2000).
Stanford, W.L., Cohn, J.B. & Cordes, S.P. Nat. Rev. Genet. 2, 756–768 (2001).
Nagy, A. Genesis 26, 99–109 (2000).
Eggan, K. et al. Proc. Natl. Acad. Sci. USA 98, 6209–6214 (2001).
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Rossant, J. Targeting mammalian genes—rats join in and mice move ahead. Nat Biotechnol 21, 625–627 (2003). https://doi.org/10.1038/nbt0603-625
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DOI: https://doi.org/10.1038/nbt0603-625
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A transgenic system for generation of transposon Ac/Ds-induced chromosome rearrangements in rice
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