Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Feature
  • Published:

Deals that make sense

By valuing and structuring their deals appropriately, biotechnology companies can earn higher returns, maintain greater control of intellectual property, and strengthen their partnerships with pharmaceutical companies.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

USD 39.95

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Financial compensation for the contributions of each deal partner.

© Bob Crimi

References

  1. An appropriate discount rate for pharma could be, for example, a pharma-marketing-specific weighted average cost of capital (WACC) of 9%. The rationale for using 9% is as follows: Grabowski and Vernon have suggested a 12% WACC for the pharmaceutical industry in general. In essence, they arrived at this figure by taking the risk-free rate of return on a 30-year US Treasury bond, which is 6%, and adding 3% for development risk and 3% for sales (market) risk. However, since we are valuing market risk here, it would be inappropriate to include development risk. Therefore, we end up with 6% (the risk-free interest rate) plus 3% (the pharma market risk), which gives a total of 9%.]

  2. Grabowski, H.G. & Vernon, J.M. A new look at the returns and risks to pharmaceutical R&D. Management Sci. 36, 804–821 (1990).

    Article  Google Scholar 

  3. Harris, G. How Merck plans to cope with patent expirations. Wall Street Journal, February 9, A1 (2000).

  4. Lerner, J. The control of technology alliances: an empirical analysis of the biotechnology industry. J. Ind. Econ. 46, 125–156 (1998).

    Article  Google Scholar 

  5. Lerner, J & Tsai, A.I. “Financing R&D through alliances: contract structure and outcomes in biotechnology” in Proceedings of Allicense '99: Banking on innovation in the next millennium (Recombinant Capital and Wilson, Sonsimi, Goodrich & Rosati, San Francisco, 1999).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Moscho, A., Hodits, R., Janus, F. et al. Deals that make sense. Nat Biotechnol 18, 719–722 (2000). https://doi.org/10.1038/77279

Download citation

  • Issue date:

  • DOI: https://doi.org/10.1038/77279

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing