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Ribozyme programming extends the protein code

Programmable ribozymes that can attach non-natural amino acids to specific tRNAs may expand the range of amino acids available for protein engineering.

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Figure 1: Aminoacylation of tRNAs with ribozymes bearing anti-anticodons.

© Bob Crimi

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Tamura, K., Schimmel, P. Ribozyme programming extends the protein code. Nat Biotechnol 20, 669–670 (2002). https://doi.org/10.1038/nbt0702-669

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