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Cytochrome P450

Caught in the act

The isolation of pure quantities of the active intermediate in cytochrome P450 enzymes — known as compound I — has led to this elusive species being characterized in detail.

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References

  1. Rittle, J. & Green, M. T. Cytochrome P450 compound I: capture, characterization, and C–H bond activation kinetics. Science 330, 933–937 (2010). 10.1126/science.1193478

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Withers, N. Caught in the act. Nature Chem (2010). https://doi.org/10.1038/nchem.953

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  • DOI: https://doi.org/10.1038/nchem.953

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