Abstract
Background A 59-year-old female presented with a history of recurrent superficial bladder cancer. Since the initial diagnosis 12 years earlier, she had had 12 recurrences, all treated with transurethral resection with adjuvant bacillus Calmette–Guérin and mitomycin C. Pathology samples had always shown Ta grade 1 transitional-cell carcinoma. At the last recurrence, she presented with several papillary lesions throughout the bladder, discovered on control cystoscopy. Transurethral resection revealed a papillary grade 3 transitional-cell carcinoma of the bladder.
Investigations Intravenous urography and ureteroscopy.
Diagnosis Panurothelial superficial transitional-cell carcinoma.
Management Radical cystectomy with total right ureterectomy and distal left ureterectomy. Reconstruction of the urinary tract was performed with the distal ileum detubulized and rearranged in a U shape. A pyeloileal anastomosis and a proximal ureteroileal anastomosis were performed at the right and left sides respectively.
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Srougi, M., Antunes, A., Dall'Oglio, M. et al. Management of panurothelial disease in superficial bladder cancer. Nat Rev Urol 3, 284–288 (2006). https://doi.org/10.1038/ncpuro0489
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DOI: https://doi.org/10.1038/ncpuro0489
