Abstract
Proximal tubule cells of the mouse kidney (metanephros) are normally extremely responsive to testosterone and its intracellular metabolites. The X-linked Tfm mutation recovered by Lyon and Hawkes seems to represent an is (repressor noninducible) mutation of the regulatory locus.
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DOFUKU, R., TETTENBORN, U. & OHNO, S. Testosterone-“Regulon” in the Mouse Kidney. Nature New Biology 232, 5–7 (1971). https://doi.org/10.1038/newbio232005a0
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DOI: https://doi.org/10.1038/newbio232005a0
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