Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letters to Editor
  • Published:

Properties of Educated T Cells for Rosette Formation and Cooperation with T Cells

Nature New Biology volume 236, pages 52–53 (1972)Cite this article

Abstract

IT has been shown that the humoral antibody response in mice to many antigens requires cooperation between thymus derived lymphocytes (T cells) and bone marrow derived lymphocytes (B cells)1,2. The B cells are the direct precursors of antibody secreting cells and, although T cells react specifically with antigen, their role is unknown2–6.

This is a preview of subscription content, access via your institution

Access options

References

  1. Claman, H. N., and Chaperon, E. A., Transplant. Rev., 1, 92 (1969).

    CAS  PubMed  Google Scholar 

  2. Miller, J. F. A. P., and Mitchell, G. F., J. Exp. Med., 128, 801 (1968).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Kettman, J., and Dutton, R. W., Proc. US Nat. Acad. Sci., 68, 699 (1971).

    Article  CAS  Google Scholar 

  4. Munro, A. J., and Hunter, P. C., Nature, 225, 227 (1970).

    Article  Google Scholar 

  5. Raff, M., Nature, 226, 1257 (1970).

    Article  CAS  PubMed  Google Scholar 

  6. Mitchison, N. A., Rajewsky, K., and Taylor, R. B., in Developmental Aspects of Antibody Formation and. Structure (edit. by Sterzl, J., and Riha, H.), 547 (Proc. Symp. Prague Czech. Acad. Sci., Academic Press, New York, 1970).

    Google Scholar 

  7. Basten, A., Miller, J. F. A. P., Warner, N. L., and Pye, J., Nature New Biology, 231, 104 (1971).

    Article  CAS  PubMed  Google Scholar 

  8. McConnell, I., Munro, A., Gurner, B. W., and Coombs, R. R. A., Intern. Arch. Allergy, 35, 209 (1969).

    Article  CAS  Google Scholar 

  9. McConnell, I., Nature New Biology, 233, 177 (1971).

    Article  CAS  PubMed  Google Scholar 

  10. Greaves, M. F., and Moller, E., Cellular Immunol., 1, 372 (1970).

    Article  CAS  Google Scholar 

  11. Schlesinger, M., Nature, 226, 1254 (1970).

    Article  CAS  PubMed  Google Scholar 

  12. Mishell, R. I., and Dutton, R. W., J. Exp. Med., 126, 423 (1967).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. Wortis, H. H., Taylor, R. B., and Dresser, D. W., Immunology, 14, 69 (1968).

    CAS  PubMed  PubMed Central  Google Scholar 

  14. Cunningham, A. J., and Szenberg, A., Immunology, 14, 599 (1968).

    CAS  PubMed  PubMed Central  Google Scholar 

  15. Hartmann, K.-U., J. Exp. Med., 132, 1267 (1970).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  16. Hartmann, K.-U., J. Exp. Med., 133 (1971).

  17. Katz, D. H., Paul, W. E., Goide, E. A., and Benacerraf, B., J. Exp. Med., 133, 169 (1971).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  18. Mosier, D. E., Science, 158, 1573 (1967).

    Article  CAS  PubMed  Google Scholar 

  19. Kincade, P. W., Lawton, A. R., and Cooper, M. D., J. Immunol., 106, 1421 (1971).

    CAS  PubMed  Google Scholar 

  20. Roberts, R. I., Brandriss, M. W., and Vaughan, J. H., J. Immunol., 106, 1056 (1971).

    CAS  PubMed  Google Scholar 

  21. Wigzell, H., Transplant. Rev., 5, 76 (1970).

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Salk Institute for Biological Studies, San Diego, California

    PHILIPPA HUNTER

  2. Department of Pathology, Tennis Court Road, Cambridge

    ALAN MUNRO

  3. Royal Postgraduate Medical School, Hammersmith Hospital, London, W12

    IAN MCCONNELL

Authors
  1. PHILIPPA HUNTER
    View author publications

    Search author on:PubMed Google Scholar

  2. ALAN MUNRO
    View author publications

    Search author on:PubMed Google Scholar

  3. IAN MCCONNELL
    View author publications

    Search author on:PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

HUNTER, P., MUNRO, A. & MCCONNELL, I. Properties of Educated T Cells for Rosette Formation and Cooperation with T Cells. Nature New Biology 236, 52–53 (1972). https://doi.org/10.1038/newbio236052a0

Download citation

  • Received:

  • Issue date:

  • DOI: https://doi.org/10.1038/newbio236052a0

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing