Abstract
ELECTRON microscopy has revealed that adrenergic axons, especially their terminal varicosities, store biogenic amines in two distinct sites, the small1,2 and the large dense core vesicles3. At present, there exists no fine structural evidence of other compartments storing amines in adrenergic axons. But biochemical and pharmacological as well as functional investigations have brought various indirect evidence suggesting that additional amine storing pools might exist4–7. Recent improvements in the technique of fixation for fine structural investigations of adrenergic neurones8 have revealed a distinct third compartment, a tubular reticulum storing endogenous biogenic monamines. A preliminary report on these findings is presented.
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References
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TRANZER, J. A New Amine Storing Compartment in Adrenergic Axons. Nature New Biology 237, 57–58 (1972). https://doi.org/10.1038/newbio237057a0
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DOI: https://doi.org/10.1038/newbio237057a0
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