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Tracing microRNA patterns in mice

MicroRNAs are important in the development of worms, flies and plants. A new study shows how the temporal and spatial expression patterns of such RNAs can be determined in mouse embryos, providing insights into the emerging role of microRNAs in Hox gene regulation.

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Figure 1: Detection of miRNAs in developing mouse embryos using 'sensor' transgenes.

Figure courtesy of Jennifer Mansfield

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Cobb, J., Duboule, D. Tracing microRNA patterns in mice. Nat Genet 36, 1033–1034 (2004). https://doi.org/10.1038/ng1004-1033

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