Supplementary Figure 8: Effects of SULT2B1 deficiency on thymocytes recognizing the HY self-antigen. | Nature Immunology

Supplementary Figure 8: Effects of SULT2B1 deficiency on thymocytes recognizing the HY self-antigen.

From: Inhibition of T cell receptor signaling by cholesterol sulfate, a naturally occurring derivative of membrane cholesterol

Supplementary Figure 8

(a) FACS plots of CD8 SP thymocytes gated on H-Y Uty Db tetramer+ populations from wild-type (WT) and Sult2b1 knock-out (KO) mice after magnetic bead enrichment. Representative data of three independent experiments are shown.

(b) The total number of the H-Y tetramer positive CD8 SP cells. Data were collected from three independent experiments. Unpaired t tests were performed (mean with SD, n=10 in male mice group, and n=8 in female mice group, P values were shown on the right).

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