Rabbits are the only animals susceptible to myxoma virus. The induction of interferon α/β by myxoma virus in nonpermissive mouse cells seems to be crucial to maintaining this species restriction.
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References
Wang, F. et al. Nat. Immunol. 5, 1266–1274 (2004).
Andrade, A.A. et al. Biochem. J. 381, 437–446 (2004).
Moss, B. in Fields Virology (eds. Knight, D.M. & Howley, P.M.) 2849–2883 (Lippincott Williams & Wilkins, Philadelphia, 2001).
Juang, Y.T. et al. Proc. Natl. Acad. Sci. USA 95, 9837–98342 (1998).
Marie, I., Durbin, J.E. & Levy, D.E. EMBO J. 17, 6660–6669 (1998).
Sato, M. et al. FEBS Lett. 441, 106–110 (1998).
Gil, M.P. et al. Proc. Natl. Acad. Sci. USA 98, 6680–6685 (2001).
Biron, C.A. & Sen, G.C. in Fields Virology (eds. Knipe, D.M. & Howley, P.M.) 321–351 (Lippincott Williams & Wilkins, 2001).
Malmgaard, L. J. Interferon Cytokine Res. 24, 439–454 (2004).
Esposito, J.J. & Fenner, F. in Fields Virology (eds. Knipe, D.M. & Howley, P.M) 2885–2921 (Lippincott Williams & Wilkins, Philadelphia, 2001).
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Vilček, J. Why are rabbits uniquely sensitive to myxoma virus? Cherchez l'interferon!. Nat Immunol 5, 1205–1206 (2004). https://doi.org/10.1038/ni1204-1205
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DOI: https://doi.org/10.1038/ni1204-1205
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